RNU6-1046P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-1046P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-1046P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-1046P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-1046P expression acts as an unfavorable survival marker, although some lineages such as BLCA and LUSC show a favorable association.

BLCA, UCS, and KIRC are the cancer types where RNU6-1046P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSTertileIII,IV0.7720.532.00196view →
UCSDFSTertileII,III,IV0.1680.493.00772view →
KIRCDFSTertileII,III,IV0.3380.584<.00166view →
ACCOSTertileII,III,IV0.1220.707<.00139view →
UCECDFSTertileIV0.2810.737.00536view →
HNSCOSTertileIII,IV0.2940.694.00336view →
CESCOSTertileIV0.2630.651.01336view →
OVOSMedianIV0.2700.491.00416view →
THYMDFSTertileII,III,IV0.4270.807.01315view →
SKCMOSTertileIV0.1790.727<.00115view →
LIHCOSTertileII,III,IV0.2330.468.02115view →
LUADOSTertileII,III,IV0.3870.615.01115view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-1046P–BLCA (DFS)

Kaplan–Meier survival curve for RNU6-1046P RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration