Q-omics provides the consensus-scored RNU11 profile across patient tissues and cancer cell-line models. RNU11 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, RNU11 is differentially expressed in 7, with the highest sampling consensus in THCA. Additionally, RNU11 RNA expression shows 7,762 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, THCA, and THYM as cancer lineages where RNU11 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU11 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU11 survival associations across molecular data types. RNU11 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU11 RNA expression–survival associations across cancer types. High RNU11 expression shows unfavorable associations in ACC, LGG, HNSC and KIRC, but favorable associations in COAD and BLCA. The COAD Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for RNU11 RNA expression.
This table summarizes RNU11 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 7. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU11. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU11 shows lower tumor expression in THCA, KICH, BLCA, PAAD, BRCA and LUAD. The THCA box plot shows higher RNU11 RNA expression in normal versus tumor tissue (log2 FC = −3.572, t-test p < 0.001).
This table shows molecular features associated with RNU11 in patient tissues and cancer cell lines. In patient samples, RNU11 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
