RNU11

Across TCGA patient cohorts, RNU11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,658 significant associations in total. THCA shows the largest number of these associations.

The most reproducible RNU11-associated GO terms across cancer lineages are Mitochondrial respiratory chain complex assembly, mRNA cis splicing, via spliceosome, and Cytoplasmic translation. Each is linked with RNU11 in more than 14 cancer types. Because this analysis shows association rather than direction, both RNU11-to-partner and partner-to-RNU11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial respiratory chain complex assembly grouped by RNU11-low versus RNU11-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU11→partner) and Y-score (partner→RNU11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mitochondrial respiratory chain complex assembly →	+0.070	+1.069	.002	<.001	3	15
TGCT	mRNA cis splicing, via spliceosome →	-0.037	-0.593	<.001	.001	3	14
ESCA	Cytoplasmic translation →	+0.094	+0.912	.001	<.001	3	13
ESCA	mRNA 3'-splice site recognition →	+0.060	+0.658	<.001	<.001	3	13
ESCA	Mitochondrial gene expression →	+0.067	+0.868	.002	<.001	2	13
ESCA	U2-type prespliceosome assembly →	+0.090	+0.830	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,658 associations by consensus.

Mitochondrial respiratory chain complex assembly by RNU11 expression — ESCA

Explore this box plot interactively →