RNA, U1 small nuclear 91, pseudogeneGenealiases: []
Q-omics provides the consensus-scored RNU1-91P profile across patient tissues and cancer cell-line models. RNU1-91P expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in LUSC. Among the 18 cancer types available for tumor–normal comparison, RNU1-91P is differentially expressed in 3, with the highest sampling consensus in KICH. Additionally, RNU1-91P RNA expression shows 10,313 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight LUSC, KICH, and THYM as cancer lineages where RNU1-91P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU1-91P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU1-91P survival associations across molecular data types. RNU1-91P RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU1-91P RNA expression–survival associations across cancer types. High RNU1-91P expression shows unfavorable associations in LUSC, UVM, KIRP, THCA, MESO and READ. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify LUSC as the clearest survival context for RNU1-91P RNA expression.
This table summarizes RNU1-91P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for RNU1-91P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU1-91P shows lower tumor expression in THCA and higher tumor expression in KICH and BLCA. The KICH box plot shows higher RNU1-91P RNA expression in tumor versus normal tissue (log2 FC = +0.225, t-test p = .008).
This table shows molecular features associated with RNU1-91P in patient tissues and cancer cell lines. In patient samples, RNU1-91P shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
