Q-omics provides the consensus-scored RNF5P1 profile across patient tissues and cancer cell-line models. RNF5P1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, RNF5P1 is differentially expressed in 4, with the highest sampling consensus in KICH. Additionally, RNF5P1 RNA expression shows 11,145 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight KIRC, KICH, and ACC as cancer lineages where RNF5P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNF5P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNF5P1 survival associations across molecular data types. RNF5P1 RNA expression shows survival associations in the most cancer types (22), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNF5P1 RNA expression–survival associations across cancer types. High RNF5P1 expression shows unfavorable associations in ACC and HNSC, but favorable associations in KIRC, SKCM, THCA and CESC. The KIRC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for RNF5P1 RNA expression.
This table summarizes RNF5P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for RNF5P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNF5P1 shows lower tumor expression in KICH and READ and higher tumor expression in KIRC and CHOL. The KICH box plot shows higher RNF5P1 RNA expression in normal versus tumor tissue (log2 FC = −1.725, t-test p < 0.001).
This table shows molecular features associated with RNF5P1 in patient tissues and cancer cell lines. In patient samples, RNF5P1 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, RNF5P1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in SOFT_TISSUE, while CRISPR and shRNA rows add functional-dependency signals in UPPER_AERODIGESTIVE_TRACT.
