RNF5P1

Across TCGA pan-cancer cohorts, RNF5P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNF5P1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNF5P1 RNA is repressed in tumor relative to normal tissue. In most cancer types RNF5P1 is over-expressed in tumor, although a few such as KICH and READ show the opposite, repressed pattern.

KICH, KIRC, and CHOL are the cancer types where RNF5P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNF5P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	All	All	−1.725	<.001	7	view →
KIRC	Female	All	+0.803	.009	3	view →
CHOL	All	II,III,IV	+0.610	.015	2	view →
READ	Female	All	−0.712	.025	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNF5P1–KICH

Open the KICH breakdown →