RNF19B

Across TCGA cell cohorts, RNF19B mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible RNF19B-associated genes across cancer lineages are SCN10A, CD300H, and PNLIP. Each is linked with RNF19B in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF19B-to-partner and partner-to-RNF19B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SCN10A grouped by RNF19B-low versus RNF19B-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF19B→partner) and Y-score (partner→RNF19B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SCN10A →	+0.004	+4.662	<.001	.005	3	1
LARGE_INTESTINE	CD300H →	+0.039	+4.415	<.001	.007	3	1
BLOOD_Leukemia	PNLIP →	+0.036	+5.539	<.001	.003	3	1
LARGE_INTESTINE	CPLX4 →	+0.029	+4.392	.001	.004	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

SCN10A by RNF19B expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →