RNF144B

Across TCGA patient cohorts, RNF144B mutation is significantly associated with the RNA expression of many other genes, with 596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF144B-associated genes across cancer lineages are RBPJP6, RNA5SP369, and VDAC3P1. Each is linked with RNF144B in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF144B-to-partner and partner-to-RNF144B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBPJP6 grouped by RNF144B-low versus RNF144B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF144B→partner) and Y-score (partner→RNF144B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RBPJP6 →	+0.025	+4.970	<.001	.005	3	2
UCEC	RNA5SP369 →	+0.328	+2.193	.001	.005	3	2
UCEC	VDAC3P1 →	+0.321	+2.364	<.001	.003	3	1
UCEC	HMGB1P50 →	+0.193	+2.092	<.001	.003	3	1
UCEC	COPS8P1 →	+0.086	+2.163	<.001	.005	3	1
UCEC	TAF9 →	+0.606	+3.700	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

RBPJP6 by RNF144B expression — SKCM

Explore this box plot interactively →