RNF144B

Across TCGA pan-cancer cohorts, RNF144B RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated RNF144B data layer compared with 4 for mutation status.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNF144B RNA is associated with better overall survival. In most high-consensus cancer types, elevated RNF144B expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRC show a favorable association.

ESCA, KIRC, and OV are the cancer types where RNF144B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	II,III,IV	0.831	0.563	<.001	84	view →
KIRC	DFS	Tertile	All	0.771	0.532	.001	54	view →
OV	DFS	Quartile	II,III,IV	0.469	0.332	.003	50	view →
LUAD	OS	Tertile	III,IV	0.677	0.313	.003	36	view →
LGG	OS	Tertile	All	0.353	0.574	.001	27	view →
UCS	DFS	Tertile	IV	0.956	0.250	.024	24	view →
LAML	DFS	Median	All	0.249	0.508	.015	22	view →
HNSC	DFS	Median	III,IV	0.717	0.496	.007	20	view →
MESO	DFS	Tertile	All	0.439	0.264	.005	18	view →
UVM	OS	Quartile	All	0.829	0.437	.014	13	view →
SCLC	OS	Quartile	II,III,IV	0.327	0.696	.009	12	view →
ACC	DFS	Quartile	III,IV	0.662	0.300	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

RNF144B–ESCA (OS)

Open the ESCA breakdown →