RNF144B

Across TCGA pan-cancer cohorts, RNF144B RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RNF144B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where RNF144B RNA is repressed in tumor relative to normal tissue. In most cancer types RNF144B is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and LUSC are the cancer types where RNF144B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNF144B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−2.826	<.001	11	view →
LUAD	Male	III,IV	−1.951	<.001	9	view →
LUSC	All	III,IV	−1.778	<.001	9	view →
BLCA	All	IV	+1.710	<.001	9	view →
THCA	All	All	−0.446	.006	4	view →
PAAD	All	All	−1.200	.014	2	view →
READ	Female	All	−1.052	.009	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RNF144B–KICH

Open the KICH breakdown →