RNF128

Across TCGA cell cohorts, RNF128 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible RNF128-associated genes across cancer lineages are OR9A2, CFAP47, and DEUP1. Each is linked with RNF128 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF128-to-partner and partner-to-RNF128 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR9A2 grouped by RNF128-low versus RNF128-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF128→partner) and Y-score (partner→RNF128) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR9A2 →	+0.016	+3.084	<.001	.002	3	2
LARGE_INTESTINE	CFAP47 →	+0.186	+3.938	.004	<.001	3	1
LARGE_INTESTINE	DEUP1 →	+0.297	+3.569	<.001	.006	3	1
LARGE_INTESTINE	MS4A7 →	+0.031	+3.464	.004	.004	3	1
LARGE_INTESTINE	MAJIN →	+0.095	+2.817	<.001	.007	3	1
LARGE_INTESTINE	OR2T33 →	+0.120	+2.716	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

OR9A2 by RNF128 expression — LARGE_INTESTINE

Explore this box plot interactively →