cilia and flagella associated protein 47Genealiases: CHDC2 · CXorf22 · CXorf30 · CXorf59 · SPGF52 · SPGFX3
Q-omics provides the consensus-scored CFAP47 profile across patient tissues and cancer cell-line models. CFAP47 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, CFAP47 is differentially expressed in 15, with the highest sampling consensus in THCA. Additionally, CFAP47 RNA expression shows 15,625 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KICH, THCA, and TGCT as cancer lineages where CFAP47 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CFAP47 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CFAP47 survival associations across molecular data types. CFAP47 RNA expression shows survival associations in the most cancer types (22), followed by mutation status (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CFAP47 RNA expression–survival associations across cancer types. High CFAP47 expression shows unfavorable associations in KICH, KIRC, ACC, DLBC and THCA, but favorable associations in LUSC. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KICH as the clearest survival context for CFAP47 RNA expression.
This table summarizes CFAP47 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for CFAP47. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CFAP47 shows lower tumor expression in THCA, LUAD and KICH and higher tumor expression in KIRC, BRCA and BLCA. The THCA box plot shows higher CFAP47 RNA expression in normal versus tumor tissue (log2 FC = −0.552, t-test p < 0.001).
This table shows molecular features associated with CFAP47 in patient tissues and cancer cell lines. In patient samples, CFAP47 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, CFAP47 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in UPPER_AERODIGESTIVE_TRACT, while CRISPR and shRNA rows add functional-dependency signals in LUNG_NSCLC_LUAD and LARGE_INTESTINE.
