CFAP47

Across TCGA patient cohorts, CFAP47 mutation is significantly associated with the RNA expression of many other genes, with 6,277 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP47-associated genes across cancer lineages are SAPCD2, MCMBP, and CCT7. Each is linked with CFAP47 in more than 5 cancer types. Because this analysis shows association rather than direction, both CFAP47-to-partner and partner-to-CFAP47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SAPCD2 grouped by CFAP47-low versus CFAP47-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP47→partner) and Y-score (partner→CFAP47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SAPCD2 →	+0.418	+1.295	.001	<.001	3	6
UCEC	MCMBP →	+0.301	+1.420	.001	<.001	3	5
UCEC	CCT7 →	+0.236	+1.495	.004	<.001	3	5
UCEC	EXO1 →	+0.374	+1.096	.005	.001	3	5
SKCM	MX2 →	-0.606	-1.675	.003	.001	3	4
UCEC	UBE2L3 →	+0.268	+1.284	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,277 associations by consensus.

SAPCD2 by CFAP47 expression — UCEC

Explore this box plot interactively →