CFAP47

Across TCGA patient cohorts, CFAP47 mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CFAP47-associated genes across cancer lineages are Caspase-7-cleavedD198, Cyclin-B1, and ASNS. Each is linked with CFAP47 in more than 4 cancer types. Because this analysis shows association rather than direction, both CFAP47-to-partner and partner-to-CFAP47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by CFAP47-low versus CFAP47-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP47→partner) and Y-score (partner→CFAP47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.763	+2.008	.017	.018	3	5
BRCA	Cyclin-B1 →	+0.696	+3.000	.023	.038	3	4
UCEC	ASNS →	+0.306	+1.253	<.001	.004	3	4
LUAD	Acetyl-a-Tubulin-Lys40 →	+0.489	+1.999	.014	.029	3	3
STAD	TFRC →	+0.684	+3.000	.034	.036	2	4
COAD	eIF4E →	+0.223	+2.725	.002	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Caspase-7-cleavedD198 by CFAP47 expression — COAD

Explore this box plot interactively →