CFAP47

Across TCGA cell cohorts, CFAP47 mutation is significantly associated with the RNA expression of many other genes, with 286 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CFAP47-associated genes across cancer lineages are MT1B, GAGE12E, and EIF3L. Each is linked with CFAP47 in more than 1 cancer types. Because this analysis shows association rather than direction, both CFAP47-to-partner and partner-to-CFAP47 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT1B grouped by CFAP47-low versus CFAP47-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CFAP47→partner) and Y-score (partner→CFAP47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	MT1B →	+0.462	+3.082	<.001	.005	3	2
LUNG_NSCLC_LUSC	GAGE12E →	+0.076	+4.643	<.001	.008	3	1
LARGE_INTESTINE	EIF3L →	+0.491	+3.257	.003	.002	3	1
LARGE_INTESTINE	CBY1 →	+0.656	+2.588	<.001	.004	3	1
LARGE_INTESTINE	CCDC113 →	+0.732	+2.588	.005	.004	3	1
LARGE_INTESTINE	R3HCC1 →	+0.677	+3.389	.005	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 286 associations by consensus.

MT1B by CFAP47 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →