RNF126

Across TCGA patient cohorts, RNF126 mutation is significantly associated with the RNA expression of many other genes, with 356 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNF126-associated genes across cancer lineages are USP9YP10, RNU6-794P, and LINC01810. Each is linked with RNF126 in more than 1 cancer types. Because this analysis shows association rather than direction, both RNF126-to-partner and partner-to-RNF126 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP10 grouped by RNF126-low versus RNF126-high in LGG.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNF126→partner) and Y-score (partner→RNF126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	2
SKCM	RNU6-794P →	+0.484	+6.219	<.001	<.001	3	2
BLCA	LINC01810 →	+0.109	+7.640	<.001	.009	3	2
COAD	SNRPCP15 →	+0.183	+4.807	<.001	.004	3	2
COAD	MIR4692 →	+1.229	+4.515	<.001	.002	3	2
LUSC	CXorf49B →	+0.044	+4.392	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 356 associations by consensus.

USP9YP10 by RNF126 expression — LGG

Explore this box plot interactively →