RNASEH2A

Across TCGA patient cohorts, RNASEH2A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,324 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RNASEH2A-associated proteins across cancer lineages are RFC2, VRK1, and MCM4. Each is linked with RNASEH2A in more than 6 cancer types. Because this analysis shows association rather than direction, both RNASEH2A-to-partner and partner-to-RNASEH2A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RNASEH2A versus RFC2 in LSCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (RNASEH2A→partner) and Y-score (partner→RNASEH2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RFC2 →	+0.426	+0.295	<.001	<.001	3	7
GBM	VRK1 →	+0.511	+0.182	<.001	<.001	3	7
LSCC	MCM4 →	+0.606	+0.215	<.001	<.001	3	6
LSCC	MCM7 →	+0.591	+0.229	<.001	<.001	3	6
LSCC	NCAPG →	+0.492	+0.226	<.001	<.001	3	6
LSCC	DNMT1 →	+0.468	+0.302	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,324 associations by consensus.

RNASEH2A vs RFC2 — LSCC

Explore this scatter interactively →