RGN

Across TCGA cell cohorts, RGN RNA expression is significantly associated with the go_rna of many other GO terms, with 942 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible RGN-associated GO terms across cancer lineages are Nuclear membrane organization, Very-low-density lipoprotein particle clearance, and Organohalogen metabolic process. Each is linked with RGN in more than 4 cancer types. Because this analysis shows association rather than direction, both RGN-to-partner and partner-to-RGN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear membrane organization grouped by RGN-low versus RGN-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RGN→partner) and Y-score (partner→RGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Nuclear membrane organization →	+0.052	+0.229	<.001	.007	3	4
LIVER	Very-low-density lipoprotein particle clearance →	+0.443	+3.487	.001	<.001	3	4
LUNG_NSCLC_LUSC	Organohalogen metabolic process →	-0.280	-0.642	<.001	.003	3	4
CNS	Regulation of proteasomal protein catabolic process →	+0.028	+0.531	.001	.002	3	4
CNS	COPII-coated vesicle budding →	+0.053	+0.461	.006	.006	3	4
BLOOD_Leukemia	Golgi vesicle transport →	+0.029	+0.098	.009	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 942 associations by consensus.

Nuclear membrane organization by RGN expression — BLOOD_Lymphoma

Explore this box plot interactively →