RFC2

Across TCGA patient cohorts, RFC2 protein abundance is significantly associated with the RNA expression of many other genes, with 21,144 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RFC2-associated genes across cancer lineages are E2F1, TTK, and KIF20A. Each is linked with RFC2 in more than 9 cancer types. Because this analysis shows association rather than direction, both RFC2-to-partner and partner-to-RFC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RFC2 versus E2F1 in LUAD, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RFC2→partner) and Y-score (partner→RFC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	E2F1 →	+1.410	+0.309	<.001	<.001	3	10
UCEC	TTK →	+1.528	+0.413	<.001	<.001	3	10
UCEC	KIF20A →	+1.391	+0.292	<.001	<.001	3	10
UCEC	LMNB1 →	+1.274	+0.323	<.001	<.001	3	10
UCEC	SMC4 →	+0.964	+0.415	<.001	<.001	3	10
UCEC	CENPA →	+1.507	+0.404	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,144 associations by consensus.

RFC2 vs E2F1 — LUAD

Explore this scatter interactively →