REV1

Across TCGA cell cohorts, REV1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible REV1-associated genes across cancer lineages are OR13H1, KIAA1210, and USP17L20. Each is linked with REV1 in more than 1 cancer types. Because this analysis shows association rather than direction, both REV1-to-partner and partner-to-REV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13H1 grouped by REV1-low versus REV1-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REV1→partner) and Y-score (partner→REV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	OR13H1 →	+0.030	+5.000	<.001	.005	3	1
KIDNEY	KIAA1210 →	+0.013	+5.000	<.001	.005	3	1
OESOPHAGUS	USP17L20 →	+0.050	+4.906	<.001	.006	3	1
OESOPHAGUS	USP17L18 →	+0.050	+4.906	<.001	.006	3	1
SKIN	TGM7 →	+0.051	+4.684	.001	.002	3	1
BLOOD_Lymphoma	OR2AK2 →	+0.043	+4.606	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

OR13H1 by REV1 expression — KIDNEY

Explore this box plot interactively →