RETN

Across TCGA patient cohorts, RETN mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. COAD shows the largest number of these associations.

The most reproducible RETN-associated genes across cancer lineages are MIR2053, UBE2V1P10, and CTDSPL2P2. Each is linked with RETN in more than 1 cancer types. Because this analysis shows association rather than direction, both RETN-to-partner and partner-to-RETN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR2053 grouped by RETN-low versus RETN-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RETN→partner) and Y-score (partner→RETN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR2053 →	+0.637	+8.066	<.001	.007	3	2
UCEC	UBE2V1P10 →	+0.154	+8.066	<.001	.007	3	1
BLCA	CTDSPL2P2 →	+0.029	+7.640	<.001	.009	3	1
COAD	RNU6-1106P →	+0.271	+7.741	<.001	.009	3	1
COAD	MIR1283-2 →	+0.392	+7.741	<.001	.009	3	1
COAD	RNU6-351P →	+0.284	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

MIR2053 by RETN expression — UCEC

Explore this box plot interactively →