REEP3

Across TCGA patient cohorts, REEP3 mutation is significantly associated with the RNA expression of many other genes, with 1,354 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible REEP3-associated genes across cancer lineages are RNU6-1213P, RNU6-1228P, and VN1R93P. Each is linked with REEP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both REEP3-to-partner and partner-to-REEP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1213P grouped by REEP3-low versus REEP3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP3→partner) and Y-score (partner→REEP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-1213P →	+0.508	+7.930	<.001	.008	3	2
UCEC	RNU6-1228P →	+0.152	+3.827	.002	.001	3	2
SKCM	VN1R93P →	+0.096	+5.292	<.001	.006	3	1
UCEC	SNRPD3 →	+0.440	+2.906	.001	.002	3	1
UCEC	PES1 →	+0.547	+3.584	.003	.002	3	1
UCEC	CRYBB3 →	+0.450	+4.032	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,354 associations by consensus.

RNU6-1213P by REEP3 expression — LUAD

Explore this box plot interactively →