REEP2

Across TCGA patient cohorts, REEP2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,906 significant associations in total. GBM shows the largest number of these associations.

The most reproducible REEP2-associated genes across cancer lineages are HS3ST2, SLC6A11, and CCDC182. Each is linked with REEP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both REEP2-to-partner and partner-to-REEP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, REEP2 versus HS3ST2 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (REEP2→partner) and Y-score (partner→REEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	HS3ST2 →	+1.329	+0.413	<.001	<.001	3	2
GBM	SLC6A11 →	+1.662	+0.372	<.001	<.001	3	2
LSCC	CCDC182 →	-0.208	-0.821	<.001	.005	3	2
GBM	FEN1P1 →	+0.543	+0.357	.003	<.001	3	2
OV	TLK2P1 →	+1.462	+0.649	.003	.006	3	2
GBM	NPM1P52 →	+0.258	+0.254	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,906 associations by consensus.

REEP2 vs HS3ST2 — GBM

Explore this scatter interactively →