Q-omics provides the consensus-scored FEN1P1 profile across patient tissues and cancer cell-line models. FEN1P1 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in OV. Among the 18 cancer types available for tumor–normal comparison, FEN1P1 is differentially expressed in 10, with the highest sampling consensus in UCEC. Additionally, FEN1P1 RNA expression shows 12,750 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight OV, UCEC, and GBM as cancer lineages where FEN1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FEN1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FEN1P1 survival associations across molecular data types. FEN1P1 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FEN1P1 RNA expression–survival associations across cancer types. High FEN1P1 expression shows unfavorable associations in LIHC, ACC, KICH, MESO and LUSC, but favorable associations in OV. The OV Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify OV as the clearest survival context for FEN1P1 RNA expression.
This table summarizes FEN1P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in UCEC for RNA.
This table ranks reproducible tumor–normal expression differences for FEN1P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FEN1P1 shows lower tumor expression in KICH and KIRC and higher tumor expression in UCEC, BRCA, COAD and LUSC. The UCEC box plot shows higher FEN1P1 RNA expression in tumor versus normal tissue (log2 FC = +0.142, t-test p = .003).
This table shows molecular features associated with FEN1P1 in patient tissues and cancer cell lines. In patient samples, FEN1P1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
