RCC1L

Across TCGA patient cohorts, RCC1L protein abundance is significantly associated with the RNA expression of many other genes, with 11,464 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RCC1L-associated genes across cancer lineages are GIMAP7, FLT3, and MNDA. Each is linked with RCC1L in more than 6 cancer types. Because this analysis shows association rather than direction, both RCC1L-to-partner and partner-to-RCC1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RCC1L versus GIMAP7 in HNSC, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCC1L→partner) and Y-score (partner→RCC1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GIMAP7 →	-0.893	-0.194	<.001	<.001	3	7
HNSC	FLT3 →	-0.689	-0.241	<.001	<.001	3	6
COAD	MNDA →	-1.116	-0.334	<.001	<.001	3	6
COAD	LRRK2 →	-0.832	-0.285	<.001	<.001	3	5
COAD	NSUN5P1 →	+0.690	+0.275	<.001	<.001	3	5
OV	FAM78A →	-0.712	-0.400	.002	.004	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,464 associations by consensus.

RCC1L vs GIMAP7 — HNSC

Explore this scatter interactively →