Q-omics provides the consensus-scored NSUN5P1 profile across patient tissues and cancer cell-line models. NSUN5P1 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, NSUN5P1 is differentially expressed in 16, with the highest sampling consensus in COAD. Additionally, NSUN5P1 RNA expression shows 16,856 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight KIRC, COAD, and UVM as cancer lineages where NSUN5P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NSUN5P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NSUN5P1 survival associations across molecular data types. NSUN5P1 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NSUN5P1 RNA expression–survival associations across cancer types. High NSUN5P1 expression shows unfavorable associations in KIRC, UVM, LIHC and LGG, but favorable associations in BLCA and UCS. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KIRC as the clearest survival context for NSUN5P1 RNA expression.
This table summarizes NSUN5P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 16. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for NSUN5P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NSUN5P1 shows higher tumor expression in COAD, KIRC, BLCA, LIHC, KICH and HNSC. The COAD box plot shows higher NSUN5P1 RNA expression in tumor versus normal tissue (log2 FC = +1.925, t-test p < 0.001).
This table shows molecular features associated with NSUN5P1 in patient tissues and cancer cell lines. In patient samples, NSUN5P1 shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set. In cancer cell lines, NSUN5P1 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in OESOPHAGUS, while CRISPR and shRNA rows add functional-dependency signals in NCI60_ALL.
