RCC1

Across TCGA patient cohorts, RCC1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,767 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible RCC1-associated genes across cancer lineages are AUNIP, KDF1, and CEP85. Each is linked with RCC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both RCC1-to-partner and partner-to-RCC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RCC1 versus AUNIP in BRCA, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RCC1→partner) and Y-score (partner→RCC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AUNIP →	+0.842	+0.330	<.001	<.001	3	7
HNSC	KDF1 →	+0.958	+0.209	<.001	<.001	3	7
HNSC	CEP85 →	+0.601	+0.176	.009	.003	2	8
HNSC	SNHG12 →	+0.817	+0.218	<.001	<.001	3	7
OV	TAF12 →	+0.556	+0.427	.001	<.001	3	6
OV	SNHG3 →	+0.684	+0.327	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,767 associations by consensus.

RCC1 vs AUNIP — BRCA

Explore this scatter interactively →