Q-omics provides the consensus-scored SNHG12 profile across patient tissues and cancer cell-line models. SNHG12 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, SNHG12 is differentially expressed in 14, with the highest sampling consensus in BLCA. Additionally, SNHG12 RNA expression shows 17,144 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and BLCA as cancer lineages where SNHG12 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for SNHG12 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes SNHG12 survival associations across molecular data types. SNHG12 RNA expression shows survival associations in the most cancer types (25). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible SNHG12 RNA expression–survival associations across cancer types. High SNHG12 expression shows unfavorable associations in ACC, KIRC, LIHC, KIRP and OV, but favorable associations in LUAD. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for SNHG12 RNA expression.
This table summarizes SNHG12 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 14. The strongest signals are observed in BLCA for RNA.
This table ranks reproducible tumor–normal expression differences for SNHG12. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. SNHG12 shows higher tumor expression in BLCA, KIRC, COAD, KIRP, LIHC and THCA. The BLCA box plot shows higher SNHG12 RNA expression in tumor versus normal tissue (log2 FC = +1.544, t-test p < 0.001).
This table shows molecular features associated with SNHG12 in patient tissues and cancer cell lines. In patient samples, SNHG12 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
