RBPJ

Across TCGA patient cohorts, RBPJ protein abundance is significantly associated with the RNA expression of many other genes, with 10,164 significant associations in total. GBM shows the largest number of these associations.

The most reproducible RBPJ-associated genes across cancer lineages are ZGRF1, HAUS3, and MED28. Each is linked with RBPJ in more than 5 cancer types. Because this analysis shows association rather than direction, both RBPJ-to-partner and partner-to-RBPJ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RBPJ versus ZGRF1 in LSCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RBPJ→partner) and Y-score (partner→RBPJ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ZGRF1 →	+0.425	+0.180	<.001	<.001	3	6
OV	HAUS3 →	+0.510	+0.214	<.001	.001	3	6
LSCC	MED28 →	+0.474	+0.296	<.001	<.001	3	6
OV	LYAR →	+0.637	+0.259	<.001	<.001	3	5
HNSC	MIR155HG →	+0.807	+0.250	<.001	<.001	3	5
GBM	PRC1-AS1 →	+0.345	+0.240	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,164 associations by consensus.

RBPJ vs ZGRF1 — LSCC

Explore this scatter interactively →