RAX2

Across TCGA patient cohorts, RAX2 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAX2-associated genes across cancer lineages are MIR4465, ELOCP14, and RNU7-88P. Each is linked with RAX2 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAX2-to-partner and partner-to-RAX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4465 grouped by RAX2-low versus RAX2-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAX2→partner) and Y-score (partner→RAX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	MIR4465 →	+0.311	+7.640	<.001	.009	3	1
COAD	ELOCP14 →	+0.139	+7.741	<.001	.009	3	1
COAD	RNU7-88P →	+0.533	+7.741	<.001	.009	3	1
UCEC	RN7SL386P →	+0.226	+4.184	.002	.003	3	1
UCEC	RNA5SP414 →	+1.017	+3.840	<.001	.007	3	1
BLCA	DEFB107B →	+0.074	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

MIR4465 by RAX2 expression — BLCA

Explore this box plot interactively →