RAP1GDS1

Across TCGA patient cohorts, RAP1GDS1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,387 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible RAP1GDS1-associated genes across cancer lineages are CNNM1, SCARB2, and WDFY3. Each is linked with RAP1GDS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both RAP1GDS1-to-partner and partner-to-RAP1GDS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, RAP1GDS1 versus CNNM1 in LSCC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAP1GDS1→partner) and Y-score (partner→RAP1GDS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CNNM1 →	-1.060	-0.240	<.001	<.001	3	4
BRCA	SCARB2 →	+0.533	+0.304	<.001	.006	3	4
BRCA	WDFY3 →	+0.408	+0.264	<.001	.006	3	4
BRCA	TSPAN5 →	+1.002	+0.331	<.001	<.001	3	4
COAD	SCFD2 →	+0.332	+0.120	<.001	.001	3	4
HNSC	NELFCD →	-0.657	-0.195	.004	.008	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,387 associations by consensus.

RAP1GDS1 vs CNNM1 — LSCC

Explore this scatter interactively →