RAB39B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RAB39B mutation is significantly associated with the RNA expression of many other genes, with 3,064 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB39B-associated genes across cancer lineages are RNU1-24P, ARHGAP42P3, and RNA5SP467. Each is linked with RAB39B in more than 2 cancer types. Because this analysis shows association rather than direction, both RAB39B-to-partner and partner-to-RAB39B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-24P grouped by RAB39B-low versus RAB39B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB39B→partner) and Y-score (partner→RAB39B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU1-24P →+0.188+4.314<.001.00933
SKCMARHGAP42P3 →+0.011+5.039<.001.00332
COADRNA5SP467 →+0.369+4.374<.001.00232
PRADLINC01784 →+0.104+7.939<.001.00832
BRCAATP5F1AP8 →+0.036+5.020<.001.00932
BLCABRD7P1 →+0.031+4.017.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,064 associations by consensus.

RNU1-24P by RAB39B expression — BLCA

Box plot of RNU1-24P in RAB39B-low vs RAB39B-high samples in BLCA.

Explore this box plot interactively →

Exploration