Q-omics provides the consensus-scored RNU1-24P profile across patient tissues and cancer cell-line models. RNU1-24P expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, RNU1-24P is differentially expressed in 1, with the highest sampling consensus in KIRC. Additionally, RNU1-24P RNA expression shows 7,720 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight UCEC, KIRC, and GBM as cancer lineages where RNU1-24P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RNU1-24P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RNU1-24P survival associations across molecular data types. RNU1-24P RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RNU1-24P RNA expression–survival associations across cancer types. High RNU1-24P expression shows unfavorable associations in UCEC, READ, DLBC, KICH, BLCA and KIRP. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify UCEC as the clearest survival context for RNU1-24P RNA expression.
This table summarizes RNU1-24P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RNU1-24P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RNU1-24P shows higher tumor expression in KIRC. The KIRC box plot shows higher RNU1-24P RNA expression in tumor versus normal tissue (log2 FC = +0.078, t-test p = .013).
This table shows molecular features associated with RNU1-24P in patient tissues and cancer cell lines. In patient samples, RNU1-24P shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
