RAB38

Across TCGA patient cohorts, RAB38 mutation is significantly associated with the RNA expression of many other genes, with 2,048 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RAB38-associated genes across cancer lineages are RNA5SP408, LIN7C, and PGAP2. Each is linked with RAB38 in more than 1 cancer types. Because this analysis shows association rather than direction, both RAB38-to-partner and partner-to-RAB38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP408 grouped by RAB38-low versus RAB38-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB38→partner) and Y-score (partner→RAB38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP408 →	+0.310	+2.486	.001	.008	3	2
UCEC	LIN7C →	+0.578	+3.365	.004	.004	3	1
UCEC	PGAP2 →	+0.487	+3.716	.001	<.001	3	1
UCEC	SSRP1 →	+0.608	+2.243	.002	.006	3	1
UCEC	LAMTOR1 →	+0.433	+2.917	.001	.001	3	1
UCEC	MTA2 →	+0.378	+2.756	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,048 associations by consensus.

RNA5SP408 by RAB38 expression — UCEC

Explore this box plot interactively →