RAB38

Across TCGA pan-cancer cohorts, RAB38 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of RAB38’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RAB38 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RAB38 is over-expressed in tumor, although a few such as PRAD and READ show the opposite, repressed pattern.

KIRP, KIRC, and THCA are the cancer types where RAB38 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RAB38 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	III,IV	+1.638	<.001	11	view →
KIRC	Male	All	+1.131	<.001	11	view →
THCA	All	III,IV	+0.730	<.001	9	view →
HNSC	All	All	+1.040	.002	7	view →
LUSC	Male	All	+1.963	<.001	6	view →
CHOL	Female	All	+3.343	<.001	5	view →
LUAD	Female	All	+0.725	<.001	5	view →
PAAD	All	All	+1.397	.047	2	view →
PRAD	All	All	−1.130	<.001	2	view →
BRCA	All	III,IV	+0.929	.035	2	view →
BLCA	All	III,IV	+1.592	.041	1	view →
READ	Female	All	−1.258	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

RAB38–KIRP

Open the KIRP breakdown →