RAB38

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, RAB38 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,008 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible RAB38-associated GO terms across cancer lineages are Regulation of phosphatidylcholine biosynthetic process, Positive regulation of phosphatidylcholine biosynthetic process, and Positive regulation of secondary metabolite biosynthetic process. Each is linked with RAB38 in more than 14 cancer types. Because this analysis shows association rather than direction, both RAB38-to-partner and partner-to-RAB38 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of phosphatidylcholine biosynthetic process grouped by RAB38-low versus RAB38-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RAB38→partner) and Y-score (partner→RAB38) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCRegulation of phosphatidylcholine biosynthetic process →-0.200-1.241<.001<.001315
LUNG_SCLCPositive regulation of phosphatidylcholine biosynthetic process →-0.200-1.241<.001<.001315
SKINPositive regulation of secondary metabolite biosynthetic process →+0.261+2.683<.001<.00139
SKINPositive regulation of melanin biosynthetic process →+0.261+2.683<.001<.00139
LUNG_NSCLC_LUSCMicroglia development →-0.213-3.064.002<.00138
PANCREASPositive regulation of cellular extravasation →+0.204+1.497<.001.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,008 associations by consensus.

Regulation of phosphatidylcholine biosynthetic process by RAB38 expression — LUNG_SCLC

Box plot of Regulation of phosphatidylcholine biosynthetic process in RAB38-low vs RAB38-high samples in LUNG_SCLC.

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Exploration