PXMP4

Across TCGA patient cohorts, PXMP4 mutation is significantly associated with the RNA expression of many other genes, with 83 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PXMP4-associated genes across cancer lineages are RNU6-1106P, RN7SL343P, and TOMM22P3. Each is linked with PXMP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both PXMP4-to-partner and partner-to-PXMP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1106P grouped by PXMP4-low versus PXMP4-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PXMP4→partner) and Y-score (partner→PXMP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-1106P →	+0.271	+7.741	<.001	.009	3	2
LUSC	RN7SL343P →	+0.144	+7.924	<.001	.008	3	2
UCEC	TOMM22P3 →	+0.126	+3.549	<.001	.003	3	2
UCEC	LINC00448 →	+0.071	+3.472	<.001	.004	3	2
COAD	H2BL1P →	+0.094	+7.741	<.001	.009	3	1
COAD	RNU6-351P →	+0.284	+7.741	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 83 associations by consensus.

RNU6-1106P by PXMP4 expression — COAD

Explore this box plot interactively →