Q-omics provides the consensus-scored LINC00448 profile across patient tissues and cancer cell-line models. LINC00448 expression is associated with patient survival in 9 of 34 cancer types, with the highest sampling consensus in LUSC. Additionally, LINC00448 RNA expression shows 5,902 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LUSC, and STAD as cancer lineages where LINC00448 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes LINC00448 survival associations across molecular data types. LINC00448 RNA expression shows survival associations in the most cancer types (9). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

LINC00448 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	9	LUSC (90)	view →

This table ranks reproducible LINC00448 RNA expression–survival associations across cancer types. High LINC00448 expression shows unfavorable associations in LUSC, BLCA, KIRP, ESCA and OV, but favorable associations in LUAD. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUSC as the clearest survival context for LINC00448 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	III,IV	0.011	0.684	<.001	90	view →
BLCA	DFS	Tertile	III,IV	0.144	0.574	<.001	54	view →
KIRP	OS	Tertile	II,III,IV	0.161	0.771	.002	42	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
OV	OS	Tertile	IV	0.028	0.759	.002	36	view →
LUAD	OS	Tertile	III,IV	0.508	0.321	.005	27	view →

Pink = unfavorable, green = favorable. all 9 lineages →

LINC00448-LUSC (OS)

Kaplan–Meier survival curve for LINC00448 RNA expression in LUSC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with LINC00448 in patient tissues and cancer cell lines. In patient samples, LINC00448 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,902	STAD (5760)	view →
RNA	3,127	STAD (1219)	view →