PWRN3

Across TCGA patient cohorts, PWRN3 RNA expression is significantly associated with the RNA expression of many other genes, with 12,790 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible PWRN3-associated genes across cancer lineages are PWRN1, NPAP1, and PWRN4. Each is linked with PWRN3 in more than 27 cancer types. Because this analysis shows association rather than direction, both PWRN3-to-partner and partner-to-PWRN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PWRN3 versus PWRN1 in PCPG, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PWRN3→partner) and Y-score (partner→PWRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PCPG	PWRN1 →	+0.943	+0.601	<.001	<.001	3	28
TGCT	NPAP1 →	+0.592	+0.334	<.001	<.001	3	24
PCPG	PWRN4 →	+0.545	+0.299	<.001	<.001	3	20
THYM	PWAR5 →	+1.458	+0.107	<.001	.003	3	18
THYM	RIC3 →	+1.046	+0.192	<.001	.006	3	17
THYM	NPTN-IT1 →	+0.932	+0.200	<.001	.003	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,790 associations by consensus.

PWRN3 vs PWRN1 — PCPG

Explore this scatter interactively →