PTPN20CP

Across TCGA patient cohorts, PTPN20CP mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible PTPN20CP-associated genes across cancer lineages are ELOCP14 and IGLVIV-53. Each is linked with PTPN20CP in more than 1 cancer types. Because this analysis shows association rather than direction, both PTPN20CP-to-partner and partner-to-PTPN20CP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELOCP14 grouped by PTPN20CP-low versus PTPN20CP-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN20CP→partner) and Y-score (partner→PTPN20CP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ELOCP14 →	+0.104	+7.816	<.001	.008	3	1
SKCM	IGLVIV-53 →	+0.094	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ELOCP14 by PTPN20CP expression — SKCM

Explore this box plot interactively →