PTPN20CP

Across TCGA pan-cancer cohorts, PTPN20CP RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of PTPN20CP’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where PTPN20CP RNA is repressed in tumor relative to normal tissue. In most cancer types PTPN20CP is over-expressed in tumor, although a few such as UCEC and KIRP show the opposite, repressed pattern.

UCEC, CHOL, and KIRP are the cancer types where PTPN20CP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in PTPN20CP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	II,III,IV	−0.133	.022	6	view →
CHOL	All	II,III,IV	+0.260	.035	2	view →
KIRP	All	II,III,IV	−0.178	.032	2	view →
THCA	All	IV	−0.060	.030	1	view →
ESCA	All	All	−0.055	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

PTPN20CP–UCEC

Open the UCEC breakdown →