Q-omics provides the consensus-scored IGLVIV-53 profile across patient tissues and cancer cell-line models. IGLVIV-53 expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in LIHC. Additionally, IGLVIV-53 RNA expression shows 7,778 significant gene co-expression associations, with the highest sampling consensus in COAD. Together, these results highlight LIHC, and COAD as cancer lineages where IGLVIV-53 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for IGLVIV-53 — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes IGLVIV-53 survival associations across molecular data types. IGLVIV-53 RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGLVIV-53 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	11	READ (72)	view →

This table ranks reproducible IGLVIV-53 RNA expression–survival associations across cancer types. High IGLVIV-53 expression shows unfavorable associations in LIHC, READ, KICH, CESC, ESCA and LUAD. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify LIHC as the clearest survival context for IGLVIV-53 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	III,IV	0.076	0.360	.001	72	view →
READ	OS	Tertile	III,IV	0.330	0.900	<.001	72	view →
KICH	DFS	Tertile	All	0.102	0.848	.004	39	view →
CESC	DFS	Tertile	All	0.184	0.823	<.001	36	view →
ESCA	OS	Tertile	All	0.198	0.872	.003	36	view →
LUAD	OS	Tertile	II,III,IV	0.150	0.677	.008	18	view →

Pink = unfavorable, green = favorable. all 11 lineages →

IGLVIV-53-LIHC (DFS)

Kaplan–Meier survival curve for IGLVIV-53 RNA expression in LIHC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGLVIV-53 in patient tissues and cancer cell lines. In patient samples, IGLVIV-53 shows the broadest associations at the RNA and protein expression levels, with COAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,778	COAD (4918)	view →
Function (RNA)	5,620	STAD (5396)	view →