IGLVIV-53

Across TCGA patient cohorts, IGLVIV-53 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,620 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGLVIV-53-associated GO terms across cancer lineages are Positive regulation of peptidase activity, Positive regulation of immune effector process, and rRNA base methylation. Each is linked with IGLVIV-53 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGLVIV-53-to-partner and partner-to-IGLVIV-53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of peptidase activity grouped by IGLVIV-53-low versus IGLVIV-53-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLVIV-53→partner) and Y-score (partner→IGLVIV-53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of peptidase activity →	+0.117	+0.054	<.001	<.001	3	5
STAD	Positive regulation of immune effector process →	+0.077	+0.053	<.001	<.001	3	5
STAD	rRNA base methylation →	+0.100	+0.049	<.001	<.001	3	5
STAD	Nucleoside triphosphate metabolic process →	+0.159	+0.056	<.001	<.001	3	5
STAD	Nucleoside triphosphate biosynthetic process →	+0.174	+0.055	<.001	<.001	3	5
STAD	Regulation of lipid localization →	+0.072	+0.048	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,620 associations by consensus.

Positive regulation of peptidase activity by IGLVIV-53 expression — STAD

Explore this box plot interactively →