PSKH1

Across TCGA patient cohorts, PSKH1 mutation is significantly associated with the RNA expression of many other genes, with 549 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PSKH1-associated genes across cancer lineages are RNVU1-24, USP9YP10, and KCNK18. Each is linked with PSKH1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PSKH1-to-partner and partner-to-PSKH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNVU1-24 grouped by PSKH1-low versus PSKH1-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PSKH1→partner) and Y-score (partner→PSKH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNVU1-24 →	+0.711	+4.268	<.001	.008	3	3
LGG	USP9YP10 →	+0.049	+7.977	<.001	.007	3	2
LUAD	KCNK18 →	+0.058	+4.631	<.001	.008	3	2
STAD	IGHVII-33-1 →	+0.264	+3.372	<.001	.007	3	2
LUSC	DUTP4 →	+0.103	+4.623	.001	.001	3	2
LUSC	RPL37P4 →	+0.275	+4.602	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 549 associations by consensus.

RNVU1-24 by PSKH1 expression — BLCA

Explore this box plot interactively →