Q-omics provides the consensus-scored DUTP4 profile across patient tissues and cancer cell-line models. DUTP4 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in READ. Among the 18 cancer types available for tumor–normal comparison, DUTP4 is differentially expressed in 2, with the highest sampling consensus in KICH. Additionally, DUTP4 RNA expression shows 7,363 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight READ, KICH, and THYM as cancer lineages where DUTP4 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for DUTP4 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes DUTP4 survival associations across molecular data types. DUTP4 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible DUTP4 RNA expression–survival associations across cancer types. High DUTP4 expression shows unfavorable associations in READ, KICH, HNSC, MESO, GBM and CHOL. The READ Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify READ as the clearest survival context for DUTP4 RNA expression.
This table summarizes DUTP4 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for DUTP4. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. DUTP4 shows higher tumor expression in KICH and KIRC. The KICH box plot shows higher DUTP4 RNA expression in tumor versus normal tissue (log2 FC = +0.089, t-test p = .020).
This table shows molecular features associated with DUTP4 in patient tissues and cancer cell lines. In patient samples, DUTP4 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
