DUTP4

Across TCGA patient cohorts, DUTP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,259 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible DUTP4-associated GO terms across cancer lineages are Tight junction organization, Transcription by RNA polymerase III, and Negative regulation of autophagy. Each is linked with DUTP4 in more than 6 cancer types. Because this analysis shows association rather than direction, both DUTP4-to-partner and partner-to-DUTP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tight junction organization grouped by DUTP4-low versus DUTP4-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DUTP4→partner) and Y-score (partner→DUTP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Tight junction organization →	+0.078	+0.023	<.001	.003	3	6
LAML	Transcription by RNA polymerase III →	+0.052	+0.037	<.001	.001	3	6
STAD	Negative regulation of autophagy →	+0.128	+0.038	<.001	.004	2	7
THYM	Autophagy of mitochondrion →	+0.065	+0.039	<.001	<.001	3	6
STAD	Regulation of generation of precursor metabolites and energy →	+0.145	+0.044	<.001	<.001	2	7
THYM	Positive regulation by host of viral genome replication →	+0.074	+0.023	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,259 associations by consensus.

Tight junction organization by DUTP4 expression — THYM

Explore this box plot interactively →