DUTP4

Across TCGA pan-cancer cohorts, DUTP4 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated DUTP4 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher DUTP4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DUTP4 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

READ, KICH, and HNSC are the cancer types where DUTP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	II,III,IV	0.111	0.919	<.001	135	view →
KICH	DFS	Tertile	All	0.585	0.921	<.001	93	view →
HNSC	OS	Tertile	II,III,IV	0.258	0.720	.001	78	view →
MESO	OS	Tertile	II,III,IV	0.121	0.571	.004	54	view →
GBM	OS	Tertile	All	0.090	0.415	<.001	45	view →
CHOL	OS	Tertile	All	0.089	0.727	.001	27	view →
UCEC	OS	Tertile	All	0.807	0.930	.005	24	view →
COAD	DFS	Tertile	IV	0.028	0.496	<.001	18	view →
LGG	DFS	Tertile	All	0.058	0.829	<.001	18	view →
OV	DFS	Tertile	All	0.651	0.528	.045	18	view →
THYM	OS	Tertile	All	0.381	0.878	.043	12	view →
BLCA	OS	Tertile	III,IV	0.230	0.585	.048	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

DUTP4–READ (OS)

Open the READ breakdown →