PRICKLE2-AS2

Across TCGA patient cohorts, PRICKLE2-AS2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,293 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PRICKLE2-AS2-associated proteins across cancer lineages are PRICKLE2_S753, PRICKLE2_S806, and RFC4. Each is linked with PRICKLE2-AS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PRICKLE2-AS2-to-partner and partner-to-PRICKLE2-AS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PRICKLE2-AS2 versus PRICKLE2_S753 in HNSC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PRICKLE2-AS2→partner) and Y-score (partner→PRICKLE2-AS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRICKLE2_S753 →	+0.730	+0.830	<.001	<.001	3	6
LSCC	PRICKLE2_S806 →	+0.836	+0.568	<.001	<.001	3	5
LSCC	RFC4 →	-0.318	-0.397	<.001	.001	3	5
LSCC	RSF1_S397 →	-0.794	-0.535	.001	.002	3	5
UCEC	SH3D19 →	+0.375	+0.726	<.001	.003	2	6
LSCC	HSPA12B_S434 →	+0.690	+0.587	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,293 associations by consensus.

PRICKLE2-AS2 vs PRICKLE2_S753 — HNSC

Explore this scatter interactively →