PPP2R5E

Across TCGA patient cohorts, PPP2R5E mutation is significantly associated with the RNA expression of many other genes, with 4,953 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PPP2R5E-associated genes across cancer lineages are PGAM1P1, SMIM11P1, and SNORD82. Each is linked with PPP2R5E in more than 2 cancer types. Because this analysis shows association rather than direction, both PPP2R5E-to-partner and partner-to-PPP2R5E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PGAM1P1 grouped by PPP2R5E-low versus PPP2R5E-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PPP2R5E→partner) and Y-score (partner→PPP2R5E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	PGAM1P1 →	+0.070	+4.867	<.001	.005	3	3
HNSC	SMIM11P1 →	+0.310	+5.912	<.001	.002	3	2
UCEC	SNORD82 →	+0.417	+1.717	<.001	.001	3	2
HNSC	HSD17B7P1 →	+0.102	+5.182	<.001	.007	3	2
HNSC	FECHP1 →	+0.087	+6.111	<.001	.002	3	2
HNSC	H2BP8 →	+0.123	+5.578	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,953 associations by consensus.

PGAM1P1 by PPP2R5E expression — SKCM

Explore this box plot interactively →