Q-omics provides the consensus-scored H2BP8 profile across patient tissues and cancer cell-line models. H2BP8 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, H2BP8 RNA expression shows 5,907 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight ESCA, and LUSC as cancer lineages where H2BP8 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes H2BP8 survival associations across molecular data types. H2BP8 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

H2BP8 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	6	ESCA (90)	view →

This table ranks reproducible H2BP8 RNA expression–survival associations across cancer types. High H2BP8 expression shows unfavorable associations in ESCA, KIRC, PAAD, STAD and PRAD, but favorable associations in HNSC. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ESCA as the clearest survival context for H2BP8 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	All	0.109	0.513	<.001	90	view →
KIRC	DFS	Tertile	II,III,IV	0.561	0.793	.004	72	view →
PAAD	OS	Tertile	All	0.172	0.616	<.001	54	view →
STAD	OS	Tertile	All	0.509	0.740	.015	18	view →
PRAD	OS	Tertile	All	0.880	0.990	<.001	18	view →
HNSC	OS	Tertile	IV	0.946	0.696	.043	6	view →

Pink = unfavorable, green = favorable. all 6 lineages →

H2BP8-ESCA (DFS)

Kaplan–Meier survival curve for H2BP8 RNA expression in ESCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with H2BP8 in patient tissues and cancer cell lines. In patient samples, H2BP8 shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	5,907	LUSC (2424)	view →
Function (RNA)	3,638	KIRC (2060)	view →